6 research outputs found
A szĂŒletĂ©si sĂșlyok megoszlĂĄsa 2011 Ă©s 2015 között Ă©s a percentilisĂ©rtĂ©kek vĂĄltozĂĄsa 1996 Ă©s 2015 között. A Tauffer-adatbĂĄzis feldolgozĂĄsa = A szĂŒletĂ©si sĂșlyok megoszlĂĄsa 2011 Ă©s 2015 között Ă©s a percentilisĂ©rtĂ©kek vĂĄltozĂĄsa 1996 Ă©s 2015 között. A Tauffer-adatbĂĄzis feldolgozĂĄsa
Absztrakt:
Bevezetés és célkitƱzés: Kutatåsi célunk a 2011 és 2015 közötti
magyarorszĂĄgi szĂŒlĂ©sek feldolgozĂĄsĂĄnak segĂtsĂ©gĂ©vel gesztĂĄciĂłs hetekre, nemekre,
valamint egyes Ă©s többes terhessĂ©gbĆl szĂŒletett magzatokra bontott aktuĂĄlis
percentiliståblåzat megalkotåsa. Emellett vizsgåltuk, hogy 1996 és 2015 között
ötĂ©ves periĂłdusokban hogyan vĂĄltoztak gesztĂĄciĂłs hetenkĂ©nt az egyes Ă©s iker fiĂș-
Ă©s leĂĄnymagzatok ĂĄtlag szĂŒletĂ©si sĂșlyai. MĂłdszer: A
MagyarorszĂĄgon kötelezĆen kitöltendĆ Ă©s vezetett Tauffer-statisztika 2011 Ă©s
2015 közötti adatai alapjån minden gesztåciós héthez kiszåmoltuk az 5, 10, 25,
50, 75, 90 és 95 percentilisértéket nemenként, egyes és ikerterhességek esetén.
VizsgĂĄltuk tovĂĄbbĂĄ a szĂŒletĂ©si sĂșlyok terhessĂ©gi hetenkĂ©nti vĂĄltozĂĄsĂĄt 1996 Ă©s
2015 között ötéves periódusokban. Eredmények: A 2011 és 2015
közötti Ă©lveszĂŒletĂ©sek sĂșly-percentilisĂ©rtĂ©keit grafikusan ĂĄbrĂĄzoltuk, Ă©s
tåblåzatokban is összefoglaltuk. A vizsgålt 20 év alatt az egyes terhességekben
a 35â41. hĂ©ten a szĂŒletĂ©si sĂșly 2011â2015-höz viszonyĂtva az 1996â2005-ig
terjedĆ idĆszakban alacsonyabb volt (a legalacsonyabb 1996â2000-ben), mĂg a
2006â2010-es periĂłdusban magasabb vagy hasonlĂł volt (pĂ©ldĂĄul a 38. hĂ©ten a
fiĂșknĂĄl 2011â2015-ben az ĂĄtlagsĂșly 3249 g, 1996â2000-ben 34,3 [SE 3,0] g-mal,
2001â2005-ben 11,5 [2,9] g-mal kevesebb, 2006â2010-ben 18,1 [2,9] g-mal több).
Az ikerterhessĂ©gekben hasonlĂł, de nem egyĂ©rtelmƱ tendenciĂĄt figyeltĂŒnk meg a
35â38. heti szĂŒletĂ©si sĂșlyokban. KövetkeztetĂ©s: Tekintettel a
szĂŒletĂ©si sĂșlyok elmĂșlt 20 Ă©vben megfigyelt jelentĆs vĂĄltozĂĄsĂĄra, szĂŒksĂ©ges az
ĂĄltalĂĄban hasznĂĄlt percentilistĂĄblĂĄzat megĂșjĂtĂĄsa. A szĂŒletĂ©si sĂșlyok 1996 Ă©s
2010 között növekedtek, elsĆsorban az Ă©rett magzatok esetĂ©n, az ezt követĆ
periĂłdusban csökkenĆ vagy stagnĂĄlĂł tendencia figyelhetĆ meg. Orv Hetil. 2019;
160(36): 1426â1436.
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Abstract:
Introduction and aim: We aimed to provide a current birth weight
percentile table for singleton and twin pregnancies stratified by gestational
week at delivery and sex using data from all live births in Hungary between 2011
and 2015. In addition, we examined temporal trends in average birth weights in
singleton and twin pregnancies by sex in five-year periods between 1996 and
2015. Method: We calculated the 5th, 10th, 25th, 50th, 75th,
90th, and 95th centiles of birth weight for each gestational week by sex for
singleton and twin pregnancies using compulsory collected obstetrical data
(Tauffer Statistics) in Hungary in 2011â2015. Furthermore, we described changes
in birth weights by gestational week between 5-year periods from 1996 to 2015.
Results: We present birth weight centiles for live births
in both tabular and graphical forms using data from 2011 to 2015. In general,
live birth weights in gestational weeks 35â41 were lower in the period of
1996â2005 (the lowest in 1996â2000) and were higher in the period of 2006â2010
compared to the reference period of 2011â2015 (e.g., the average male newborn
weighed 3249 g at gestational week 38 in 2011â2015, which is 34.3 [SE at 3.0] g
less in 1996â2000, 11.5 [2.9] g less in 2001â2005, and 18.1 [2.9] g more in
2006â2010). Similar trends were not observed in birth weights of twin
pregnancies in gestational weeks 35â38. Conclusion: Given the
observed substantial change in birth weights during the past 20 years, renewal
of the commonly used percentile tables is necessary. Birth weights increased
from 1996 to 2010, mainly of mature newborns, followed by a stabilization or
slight decrease in the later periods. Orv Hetil. 2019; 160(36): 1426â1436
Pregnancy outcomes of women with untreated âmildâ gestational diabetes (gestational diabetes by the WHO 2013 but not by the WHO-1999 diagnostic criteria) â A population-based cohort study
AIMS: We compared pregnancy outcomes of untreated 'mild' GDM (GDM by WHO 2013 but not by WHO-1999) to normal glucose tolerant women (NGT). METHODS: In a universal screening program 4333 pregnant women had a 3-point 75 g OGTT in Hungary in 2009-2013. By WHO-2013 untreated NGT was diagnosed in n = 3303, 'mild' GDM in n = 336 cases. RESULTS: 'Mild' GDM women were older (mean difference, SE: 1.4, 0.3 yrs), had higher fasting (1.0, 0.02), 60-minute (1.0, 0.09), and 120-minute (0.4, 0.06 mmol/l) blood glucose, and blood pressure (2.6, 0.5/2.0, 0.5 mmHg). Weight gain was similar in both groups (-0.3, 0.3 kg). GDM newborns were heavier (142, 50 g) and were more frequently macrosomic (>4000 g, OR 1.85, 95 %CI 1.35-2.54). Hypertension during pregnancy was more prevalent in the GDM group (OR 1.55, 95 %CI 1.05-2.28), as well as induced (OR 1.38, 95 %CI 1.10-1.74) and instrumental delivery (OR 1.34, 95 %CI 1.07-1.68), and acute caesarean section (OR 1.32, 95 %CI 1.04-1.64). Most of these differences substantially attenuated or became non-significant after adjustment for pre-pregnancy BMI. CONCLUSIONS: Pregnancy outcomes of 'mild' GDM were worse compared to normal glucose tolerant women however these differences were explained by the pre-pregnancy BMI difference between groups
Trend of pregnancy outcomes in type 1 diabetes compared to control women: a register-based analysis in 1996-2018
INTRODUCTION: In 1989, the St Vincent declaration aimed to approximate pregnancy outcomes of diabetes to that of healthy pregnancies. We aimed to compare frequency and trends of outcomes of pregnancies affected by type 1 diabetes and controls in 1996-2018. METHODS: We used anonymized records of a mandatory nation-wide registry of all deliveries between gestational weeks 24 and 42 in Hungary. We included all singleton births (4,091 type 1 diabetes, 1,879,183 controls) between 1996 and 2018. We compared frequency and trends of pregnancy outcomes between type 1 diabetes and control pregnancies using hierarchical Poisson regression. RESULTS: The frequency of stillbirth, perinatal mortality, large for gestational age, caesarean section, admission to neonatal intensive care unit (NICU), and low Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score was 2-4 times higher in type 1 diabetes compared to controls, while the risk of congenital malformations was increased by 51% and SGA was decreased by 42% (all p<0.05). These observations remained significant after adjustment for confounders except for low APGAR scores. We found decreasing rate ratios comparing cases and controls over time for caesarean sections, low APGAR scores (p<0.05), and for NICU admissions (p=0.052) in adjusted models. The difference between cases and controls became non-significant after 2009. No linear trends were observed for the other outcomes. CONCLUSIONS: Although we found that the rates of SGA, NICU care, and low APGAR score improved in pregnancies complicated by type 1 diabetes, the target of the St Vincent Declaration was only achieved for the occurrence of low APGAR scores